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Triple Therapy Protocol for Primary and Secondary Auricular Keloids: A Prospective Outcome Evaluation
BACKGROUND: Ear keloid lesions present a significant challenge to the aesthetic surgeon. Keloids are known to recur and can cause severe cosmetic, functional, and psychological impairments. Several adjuvants to surgical removal have been promoted, with varying recurrence rates. OBJECTIVE: To evaluat...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461721/ https://www.ncbi.nlm.nih.gov/pubmed/37399134 http://dx.doi.org/10.1097/DSS.0000000000003867 |
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author | Datema, Frank R. Saridin, Joan Timmer, Ferdinand C.A. Rothuizen, Laura T. van Zijl, Floris V.W.J. |
author_facet | Datema, Frank R. Saridin, Joan Timmer, Ferdinand C.A. Rothuizen, Laura T. van Zijl, Floris V.W.J. |
author_sort | Datema, Frank R. |
collection | PubMed |
description | BACKGROUND: Ear keloid lesions present a significant challenge to the aesthetic surgeon. Keloids are known to recur and can cause severe cosmetic, functional, and psychological impairments. Several adjuvants to surgical removal have been promoted, with varying recurrence rates. OBJECTIVE: To evaluate the effectiveness of triple therapy to treat secondary (and large primary) auricular keloids. MATERIALS AND METHODS: Patients with secondary or large primary auricular keloids undergoing triple therapy were prospectively studied. Keloids were excised intramarginally under magnification and repeated triamcinolone acetonide 40 mg/mL injections were administered, followed by the application of a custom-made acrylate pressure device. Recurrent keloid formation and adverse events were monitored during a minimum of 6 months of follow-up. RESULTS: Sixteen auricular keloid lesions (3 large primary and 13 secondary) were subjected to the proposed technique with a mean follow-up of 28 months. All cases that adhered to the protocol were free of keloid after triple therapy. Side effects were limited to 1 case of lobular atrophy and slight hypopigmentation. All patients were satisfied with the results. CONCLUSION: The triple therapy protocol is highly effective in primary and secondary auricular keloid as long as patients remain compliant. |
format | Online Article Text |
id | pubmed-10461721 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-104617212023-08-29 Triple Therapy Protocol for Primary and Secondary Auricular Keloids: A Prospective Outcome Evaluation Datema, Frank R. Saridin, Joan Timmer, Ferdinand C.A. Rothuizen, Laura T. van Zijl, Floris V.W.J. Dermatol Surg Original Article BACKGROUND: Ear keloid lesions present a significant challenge to the aesthetic surgeon. Keloids are known to recur and can cause severe cosmetic, functional, and psychological impairments. Several adjuvants to surgical removal have been promoted, with varying recurrence rates. OBJECTIVE: To evaluate the effectiveness of triple therapy to treat secondary (and large primary) auricular keloids. MATERIALS AND METHODS: Patients with secondary or large primary auricular keloids undergoing triple therapy were prospectively studied. Keloids were excised intramarginally under magnification and repeated triamcinolone acetonide 40 mg/mL injections were administered, followed by the application of a custom-made acrylate pressure device. Recurrent keloid formation and adverse events were monitored during a minimum of 6 months of follow-up. RESULTS: Sixteen auricular keloid lesions (3 large primary and 13 secondary) were subjected to the proposed technique with a mean follow-up of 28 months. All cases that adhered to the protocol were free of keloid after triple therapy. Side effects were limited to 1 case of lobular atrophy and slight hypopigmentation. All patients were satisfied with the results. CONCLUSION: The triple therapy protocol is highly effective in primary and secondary auricular keloid as long as patients remain compliant. Lippincott Williams & Wilkins 2023-09 2023-07-03 /pmc/articles/PMC10461721/ /pubmed/37399134 http://dx.doi.org/10.1097/DSS.0000000000003867 Text en Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Society for Dermatologic Surgery, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Datema, Frank R. Saridin, Joan Timmer, Ferdinand C.A. Rothuizen, Laura T. van Zijl, Floris V.W.J. Triple Therapy Protocol for Primary and Secondary Auricular Keloids: A Prospective Outcome Evaluation |
title | Triple Therapy Protocol for Primary and Secondary Auricular Keloids: A Prospective Outcome Evaluation |
title_full | Triple Therapy Protocol for Primary and Secondary Auricular Keloids: A Prospective Outcome Evaluation |
title_fullStr | Triple Therapy Protocol for Primary and Secondary Auricular Keloids: A Prospective Outcome Evaluation |
title_full_unstemmed | Triple Therapy Protocol for Primary and Secondary Auricular Keloids: A Prospective Outcome Evaluation |
title_short | Triple Therapy Protocol for Primary and Secondary Auricular Keloids: A Prospective Outcome Evaluation |
title_sort | triple therapy protocol for primary and secondary auricular keloids: a prospective outcome evaluation |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461721/ https://www.ncbi.nlm.nih.gov/pubmed/37399134 http://dx.doi.org/10.1097/DSS.0000000000003867 |
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