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An objective criterion to evaluate sequence-similarity networks helps in dividing the protein family sequence space
The deluge of genomic data raises various challenges for computational protein annotation. The definition of superfamilies, based on conserved folds, or of families, showing more recent homology signatures, allow a first categorization of the sequence space. However, for precise functional annotatio...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461819/ https://www.ncbi.nlm.nih.gov/pubmed/37585436 http://dx.doi.org/10.1371/journal.pcbi.1010881 |