Multi-ancestry GWAS analysis identifies two novel loci associated with diabetic eye disease and highlights APOL1 as a high risk locus in patients with diabetic macular edema

Diabetic retinopathy (DR) is a common complication of diabetes. Approximately 20% of DR patients have diabetic macular edema (DME) characterized by fluid leakage into the retina. There is a genetic component to DR and DME risk, but few replicable loci. Because not all DR cases have DME, we focused o...

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Detalles Bibliográficos
Autores principales: Stockwell, Amy D., Chang, Michael C., Mahajan, Anubha, Forrest, William, Anegondi, Neha, Pendergrass, Rion K., Selvaraj, Suresh, Reeder, Jens, Wei, Eric, Iglesias, Victor A., Creps, Natalie M., Macri, Laura, Neeranjan, Andrea N., van der Brug, Marcel P., Scales, Suzie J., McCarthy, Mark I., Yaspan, Brian L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461827/
https://www.ncbi.nlm.nih.gov/pubmed/37585454
http://dx.doi.org/10.1371/journal.pgen.1010609

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