Role of hepcidin upregulation and proteolytic cleavage of ferroportin 1 in hepatitis C virus-induced iron accumulation

Hepatitis C virus (HCV) is a pathogen characterized not only by its persistent infection leading to the development of cirrhosis and hepatocellular carcinoma (HCC), but also by metabolic disorders such as lipid and iron dysregulation. Elevated iron load is commonly observed in the livers of patients...

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Detalles Bibliográficos
Autores principales: Ohta, Kazuyoshi, Ito, Masahiko, Chida, Takeshi, Nakashima, Kenji, Sakai, Satoshi, Kanegae, Yumi, Kawasaki, Hideya, Aoshima, Takuya, Takabayashi, Shuji, Takahashi, Hirotaka, Kawata, Kazuhito, Shoji, Ikuo, Sawasaki, Tatsuya, Suda, Takafumi, Suzuki, Tetsuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461841/
https://www.ncbi.nlm.nih.gov/pubmed/37585449
http://dx.doi.org/10.1371/journal.ppat.1011591

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