MIM-CyCIF: Masked Imaging Modeling for Enhancing Cyclic Immunofluorescence (CyCIF) with Panel Reduction and Imputation

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CyCIF quantifies multiple biomarkers, but panel capacity is compromised by technical challenges including tissue loss. We propose a computational panel reduction, inferring surrogate CyCIF data from a subset of biomarkers. Our model reconstructs the information content from 25 markers using only 9 m...

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Detalles Bibliográficos
Autores principales: Sims, Zachary, Mills, Gordon B., Chang, Young Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461912/
https://www.ncbi.nlm.nih.gov/pubmed/37645765
http://dx.doi.org/10.1101/2023.05.10.540265

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