Cargando…
Differences in Conformational Sampling and Intrinsic Electric Fields Drive Ion Binding in Telomeric and TERRA G-Quadruplexes
The formation of G-quadruplexes (GQs) occurs in guanine-rich sequences of DNA and RNA, producing highly stable and structurally diverse noncanonical nucleic acid structures. GQs play crucial roles in regulating transcription, translation, and replication; and maintaining the genome, among others, th...
Autores principales: | Polêto, Marcelo D., Lemkul, Justin A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461924/ https://www.ncbi.nlm.nih.gov/pubmed/37645825 http://dx.doi.org/10.1101/2023.08.10.552810 |
Ejemplares similares
-
Same fold, different properties: polarizable molecular dynamics simulations of telomeric and TERRA G-quadruplexes
por: Lemkul, Justin A
Publicado: (2020) -
Ion-Dependent Conformational Plasticity of Telomeric
G-Hairpins and G-Quadruplexes
por: Salsbury, Alexa M., et al.
Publicado: (2022) -
Integration of experimental data and use of automated fitting methods in developing protein force fields
por: Polêto, Marcelo D., et al.
Publicado: (2022) -
A crystallographic and modelling study of a human telomeric RNA (TERRA) quadruplex
por: Collie, Gavin W., et al.
Publicado: (2010) -
TERRA G-quadruplex RNA interaction with TRF2 GAR domain is required for telomere integrity
por: Mei, Yang, et al.
Publicado: (2021)