ATG2A-mediated bridge-like lipid transport regulates lipid droplet accumulation

ATG2 proteins facilitate bulk lipid transport between membranes. ATG2 is an essential autophagy protein, but ATG2 also localizes to lipid droplets (LDs), and genetic depletion of ATG2 increases LD numbers while impairing fatty acid transport from LDs to mitochondria. How ATG2 supports LD homeostasis...

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Detalles Bibliográficos
Autores principales: Korfhage, Justin L., Wan, Neng, Elhan, Helin, Kauffman, Lisa, Pineda, Mia, Fuller, Devin M., Thiam, Abdou Rachid, Reinisch, Karin M., Melia, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461963/
https://www.ncbi.nlm.nih.gov/pubmed/37645754
http://dx.doi.org/10.1101/2023.08.14.553257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461963/
https://www.ncbi.nlm.nih.gov/pubmed/37645754
http://dx.doi.org/10.1101/2023.08.14.553257

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