Multi-omic stratification of the missense variant cysteinome

Cancer genomes are rife with genetic variants; one key outcome of this variation is gain-ofcysteine, which is the most frequently acquired amino acid due to missense variants in COSMIC. Acquired cysteines are both driver mutations and sites targeted by precision therapies. However, despite their ubi...

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Detalles Bibliográficos
Autores principales: Desai, Heta, Ofori, Samuel, Boatner, Lisa, Yu, Fengchao, Villanueva, Miranda, Ung, Nicholas, Nesvizhskii, Alexey I., Backus, Keriann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461992/
https://www.ncbi.nlm.nih.gov/pubmed/37645963
http://dx.doi.org/10.1101/2023.08.12.553095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461992/
https://www.ncbi.nlm.nih.gov/pubmed/37645963
http://dx.doi.org/10.1101/2023.08.12.553095

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