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Multi-omic stratification of the missense variant cysteinome
Cancer genomes are rife with genetic variants; one key outcome of this variation is gain-ofcysteine, which is the most frequently acquired amino acid due to missense variants in COSMIC. Acquired cysteines are both driver mutations and sites targeted by precision therapies. However, despite their ubi...
Autores principales: | Desai, Heta, Ofori, Samuel, Boatner, Lisa, Yu, Fengchao, Villanueva, Miranda, Ung, Nicholas, Nesvizhskii, Alexey I., Backus, Keriann |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461992/ https://www.ncbi.nlm.nih.gov/pubmed/37645963 http://dx.doi.org/10.1101/2023.08.12.553095 |
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