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An eQTL-based Approach Reveals Candidate L1 Transcriptional Regulators in Lymphoblastoid Cells

Long interspersed element 1 (L1) are a family of autonomous, actively mobile transposons that occupy ~17% of the human genome. The pleiotropic effects L1 induces in host cells (promoting genome instability, inflammation, or cellular senescence) are established, and L1’s associations with aging and a...

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Detalles Bibliográficos
Autores principales: Bravo, Juan I., Mizrahi, Chanelle R., Kim, Seungsoo, Zhang, Lucia, Suh, Yousin, Benayoun, Bérénice A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461994/
https://www.ncbi.nlm.nih.gov/pubmed/37645920
http://dx.doi.org/10.1101/2023.08.15.553416