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An eQTL-based Approach Reveals Candidate L1 Transcriptional Regulators in Lymphoblastoid Cells
Long interspersed element 1 (L1) are a family of autonomous, actively mobile transposons that occupy ~17% of the human genome. The pleiotropic effects L1 induces in host cells (promoting genome instability, inflammation, or cellular senescence) are established, and L1’s associations with aging and a...
Autores principales: | Bravo, Juan I., Mizrahi, Chanelle R., Kim, Seungsoo, Zhang, Lucia, Suh, Yousin, Benayoun, Bérénice A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10461994/ https://www.ncbi.nlm.nih.gov/pubmed/37645920 http://dx.doi.org/10.1101/2023.08.15.553416 |
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