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DISSECTING TUMOR TRANSCRIPTIONAL HETEROGENEITY FROM SINGLE-CELL RNA-SEQ DATA BY GENERALIZED BINARY COVARIANCE DECOMPOSITION

Profiling tumors with single-cell RNA sequencing (scRNA-seq) has the potential to identify recurrent patterns of transcription variation related to cancer progression, and so produce new therapeutically-relevant insights. However, the presence of strong inter-tumor heterogeneity often obscures more...

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Detalles Bibliográficos
Autores principales:	Liu, Yusha, Carbonetto, Peter, Willwerscheid, Jason, Oakes, Scott A., Macleod, Kay F., Stephens, Matthew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462040/ https://www.ncbi.nlm.nih.gov/pubmed/37645713 http://dx.doi.org/10.1101/2023.08.15.553436

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