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A tryptophan metabolite modulates the host response to bacterial infection via kainate receptors

Bacterial infection involves a complex interaction between the pathogen and host where the outcome of infection is not solely determined by pathogen eradication. To identify small molecules that promote host survival by altering the host-pathogen dynamic, we conducted an in vivo chemical screen usin...

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Detalles Bibliográficos
Autores principales: Parada-Kusz, Margarita, Clatworthy, Anne E., Goering, Emily R., Blackwood, Stephanie M., Salm, Elizabeth J., Choi, Catherine, Combs, Senya, Lee, Jenny S. W., Rodriguez-Osorio, Carlos, Tomita, Susumu, Hung, Deborah T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462041/
https://www.ncbi.nlm.nih.gov/pubmed/37645903
http://dx.doi.org/10.1101/2023.08.16.553532