Reduced PIN1 gene expression in neocortical and limbic brain regions in female Alzheimer’s patients correlates with cognitive and neuropathological phenotypes

Women have a higher incidence of Alzheimer’s disease (AD), even after adjusting for increased longevity. Thus, there is an urgent need to identify the molecular networks that underpin the sex-associated risk of AD. Recent efforts have identified PIN1 as a key regulator of tau phosphorylation signali...

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Detalles Bibliográficos
Autores principales: de Ávila, Camila, Suazo, Crystal, Nolz, Jennifer, Cochran, J. Nicholas, Wang, Qi, Velazquez, Ramon, Dammer, Eric, Readhead, Benjamin, Mastroeni, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462057/
https://www.ncbi.nlm.nih.gov/pubmed/37645898
http://dx.doi.org/10.1101/2023.08.14.553279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462057/
https://www.ncbi.nlm.nih.gov/pubmed/37645898
http://dx.doi.org/10.1101/2023.08.14.553279

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