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A non-canonical mechanism of GPCR activation

The goal of designing safer, more effective drugs has led to tremendous interest in molecular mechanisms through which ligands can precisely manipulate signaling of G-protein-coupled receptors (GPCRs), the largest class of drug targets. Decades of research have led to the widely accepted view that a...

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Detalles Bibliográficos
Autores principales: Powers, Alexander S., Khan, Aasma, Paggi, Joseph M., Latorraca, Naomi R., Souza, Sarah, Salvo, Jerry Di, Lu, Jun, Soisson, Stephen M., Johnston, Jennifer M., Weinglass, Adam B., Dror, Ron O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462065/
https://www.ncbi.nlm.nih.gov/pubmed/37645874
http://dx.doi.org/10.1101/2023.08.14.553154

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