Triaging of α-helical proteins to the mitochondrial outer membrane by distinct chaperone machinery based on substrate topology

Mitochondrial outer membrane α-helical proteins play critical roles in mitochondrial-cytoplasmic communication, but the rules governing the targeting and insertion of these biophysically diverse substrates remain unknown. Here, we first defined the complement of required mammalian biogenesis machine...

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Detalles Bibliográficos
Autores principales: Muthukumar, Gayathri, Stevens, Taylor A., Inglis, Alison J., Esantsi, Theodore K., Saunders, Reuben A., Schulte, Fabian, Voorhees, Rebecca M., Guna, Alina, Weissman, Jonathan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462106/
https://www.ncbi.nlm.nih.gov/pubmed/37645817
http://dx.doi.org/10.1101/2023.08.16.553624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462106/
https://www.ncbi.nlm.nih.gov/pubmed/37645817
http://dx.doi.org/10.1101/2023.08.16.553624

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