Triaging of α-helical proteins to the mitochondrial outer membrane by distinct chaperone machinery based on substrate topology

Mitochondrial outer membrane α-helical proteins play critical roles in mitochondrial-cytoplasmic communication, but the rules governing the targeting and insertion of these biophysically diverse substrates remain unknown. Here, we first defined the complement of required mammalian biogenesis machine...

Descripción completa

Detalles Bibliográficos
Autores principales: Muthukumar, Gayathri, Stevens, Taylor A., Inglis, Alison J., Esantsi, Theodore K., Saunders, Reuben A., Schulte, Fabian, Voorhees, Rebecca M., Guna, Alina, Weissman, Jonathan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462106/
https://www.ncbi.nlm.nih.gov/pubmed/37645817
http://dx.doi.org/10.1101/2023.08.16.553624

Ejemplares similares

Ejemplares similares