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ATP Mediates Phase Separation of Disordered Basic Proteins by Bridging Intermolecular Interaction Networks
ATP is an abundant molecule with crucial cellular roles as the energy currency and a building block of nucleic acids and for protein phosphorylation. Here we show that ATP mediates the phase separation of basic intrinsically disordered proteins (bIDPs). In the resulting condensates, ATP is highly co...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462115/ https://www.ncbi.nlm.nih.gov/pubmed/37645809 http://dx.doi.org/10.1101/2023.08.20.554035 |