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Formation of templated inclusions in a forebrain α-synuclein mouse model is independent of LRRK2

Leucine-rich repeat kinase 2 (LRRK2) and α-synuclein share enigmatic roles in the pathobiology of Parkinson’s disease (PD). LRRK2 mutations are a common genetic cause of PD which, in addition to neurodegeneration, often present with abnormal deposits of α-synuclein in the form of Lewy-related pathol...

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Detalles Bibliográficos
Autores principales:	Dues, Dylan J., Ma, Yue, Nguyen, An Phu Tran, Offerman, Alina V., Beddows, Ian, Moore, Darren J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462117/ https://www.ncbi.nlm.nih.gov/pubmed/37645723 http://dx.doi.org/10.1101/2023.08.19.553965

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