Insights into RAG evolution from the identification of “missing link” family A RAGL transposons

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A series of “molecular domestication” events are thought to have converted an invertebrate RAG-like (RAGL) transposase into the RAG1-RAG2 (RAG) recombinase, a critical enzyme for adaptive immunity in jawed vertebrates. The timing and order of these events is not well understood, in part because of a...

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Detalles Bibliográficos
Autores principales: Martin, Eliza C., Le Targa, Lorlane, Tsakou-Ngouafo, Louis, Fan, Tzu-Pei, Lin, Che-Yi, Xiao, Jianxiong, Su, Yi Hsien, Petrescu, Andrei-Jose, Pontarotti, Pierre, Schatz, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462144/
https://www.ncbi.nlm.nih.gov/pubmed/37645967
http://dx.doi.org/10.1101/2023.08.20.553239
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