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Molecular Dynamics Simulation of Apolipoprotein E3 Lipid Nanodiscs

Nanodiscs are binary discoidal complexes of a phospholipid bilayer circumscribed by belt-like helical scaffold proteins. Using coarse-grained and all-atom molecular dynamics simulations, we explore the stability, size, and structure of nanodiscs formed between the N-terminal domain of apolipoprotein...

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Detalles Bibliográficos
Autores principales: Allen, Patrick, Smith, Adam C., Benedicto, Vernon, Abdulhassan, Abbas, Narayanaswami, Vasanthy, Tapavicza, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cornell University 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462174/
https://www.ncbi.nlm.nih.gov/pubmed/37645042