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Molecular Dynamics Simulation of Apolipoprotein E3 Lipid Nanodiscs
Nanodiscs are binary discoidal complexes of a phospholipid bilayer circumscribed by belt-like helical scaffold proteins. Using coarse-grained and all-atom molecular dynamics simulations, we explore the stability, size, and structure of nanodiscs formed between the N-terminal domain of apolipoprotein...
Autores principales: | Allen, Patrick, Smith, Adam C., Benedicto, Vernon, Abdulhassan, Abbas, Narayanaswami, Vasanthy, Tapavicza, Enrico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cornell University
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462174/ https://www.ncbi.nlm.nih.gov/pubmed/37645042 |
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