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LFSPROShiny: an interactive R/Shiny app for prediction and visualization of cancer risks in families with deleterious germline TP53 mutations

PURPOSE: LFSPRO is an R library that implements risk prediction models for Li-Fraumeni syndrome (LFS), a genetic disorder characterized by deleterious germline mutations in the TP53 gene. To facilitate the use of these models in clinics, we developed LFSPROShiny, an interactive R/Shiny interface of...

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Detalles Bibliográficos
Autores principales:	Nguyen, Nam H, Dodd-Eaton, Elissa B, Peng, Gang, Corredor, Jessica L., Jiao, Wenwei, Woodman-Ross, Jacynda, Arun, Banu K., Wang, Wenyi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462184/ https://www.ncbi.nlm.nih.gov/pubmed/37645796 http://dx.doi.org/10.1101/2023.08.11.23293956

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