Genetic evidence for serum amyloid P component as a drug target for treatment of neurodegenerative disorders

The direct causes of neurodegeneration underlying Alzheimer’s disease (AD) and many other dementias, are not known. Here we identify serum amyloid P component (SAP), a constitutive plasma protein normally excluded from the brain, as a potential drug target. After meta-analysis of three genome-wide a...

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Detalles Bibliográficos
Autores principales: Schmidt, A Floriaan, Finan, Chris, Chopade, Sandesh, Ellmerich, Stephan, Rossor, Martin N, Hingorani, Aroon D, Pepys, Mark B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462209/
https://www.ncbi.nlm.nih.gov/pubmed/37645746
http://dx.doi.org/10.1101/2023.08.15.23293564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462209/
https://www.ncbi.nlm.nih.gov/pubmed/37645746
http://dx.doi.org/10.1101/2023.08.15.23293564

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