The replication-competent HIV reservoir is a genetically restricted, younger subset of the overall pool of HIV proviruses persisting during therapy, which is highly genetically stable over time

Within-host HIV populations continually diversify during untreated infection, and members of these diverse forms persist within infected cell reservoirs, even during antiretroviral therapy (ART). Characterizing the diverse viral sequences that persist during ART is critical to HIV cure efforts, but...

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Detalles Bibliográficos
Autores principales: Shahid, Aniqa, MacLennan, Signe, Jones, Bradley R., Sudderuddin, Hanwei, Dang, Zhong, Cobamibias, Kyle, Duncan, Maggie C., Kinloch, Natalie N., Dapp, Michael J., Archin, Nande M, Fischl, Margaret A., Ofotokun, Igho, Adimora, Adaora, Gange, Stephen, Aouizerat, Bradley, Kuniholm, Mark H., Kassaye, Seble, Mullins, James I., Goldstein, Harris, Joy, Jeffrey B., Anastos, Kathryn, Brumme, Zabrina L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462229/
https://www.ncbi.nlm.nih.gov/pubmed/37645749
http://dx.doi.org/10.21203/rs.3.rs-3259040/v1

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