Turning anecdotal irradiation-induced anti-cancer immune responses into reproducible in situ cancer vaccines via disulfiram/copper-mediated enhanced immunogenic cell death of breast cancer cells

Irradiation (IR) induces immunogenic cell death (ICD) in tumors, but it rarely leads to the abscopal effect (AE). However, combining IR with immune checkpoint inhibitors has shown anecdotal success in inducing AEs. In this study, we aimed to enhance the IR-induced immune response and generate reprod...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Xinhui, Guo, Wei, Jia, Lin, Xie, Ling, Kiang, Juliann, Wang, Yangyang, Wang, Fuyou, Lin, Zunwen, Wang, Enwen, Zhang, Yida, Huang, Peigen, Sun, Ting, Zhang, Xiao, Bian, Zhengying, Tang, Tiejun, Guo, Jingtian, Ferrone, Soldano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462241/
https://www.ncbi.nlm.nih.gov/pubmed/37645899
http://dx.doi.org/10.21203/rs.3.rs-3195392/v1

Ejemplares similares

Ejemplares similares