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Machine Learning-driven Fragment-based Discovery of CIB1-directed Anti-Tumor Agents by FRASE-bot

Chemical probes are an indispensable tool for translating biological discoveries into new therapies, though are increasingly difficult to identify. Novel therapeutic targets are often hard-to-drug proteins, such as messengers or transcription factors. Computational strategies arise as a promising so...

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Detalles Bibliográficos
Autores principales: An, Yi, Glavatskikh, Marta, Lim, Jiwoong, Wang, Xiaowen, Norris-Drouin, Jacqueline, Hardy, P. Brian, Leisner, Tina M., Pearce, Kenneth H., Kireev, Dmitri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462244/
https://www.ncbi.nlm.nih.gov/pubmed/37645935
http://dx.doi.org/10.21203/rs.3.rs-3197490/v1