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Machine Learning-driven Fragment-based Discovery of CIB1-directed Anti-Tumor Agents by FRASE-bot
Chemical probes are an indispensable tool for translating biological discoveries into new therapies, though are increasingly difficult to identify. Novel therapeutic targets are often hard-to-drug proteins, such as messengers or transcription factors. Computational strategies arise as a promising so...
Autores principales: | An, Yi, Glavatskikh, Marta, Lim, Jiwoong, Wang, Xiaowen, Norris-Drouin, Jacqueline, Hardy, P. Brian, Leisner, Tina M., Pearce, Kenneth H., Kireev, Dmitri |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462244/ https://www.ncbi.nlm.nih.gov/pubmed/37645935 http://dx.doi.org/10.21203/rs.3.rs-3197490/v1 |
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