MIB Guides: Preclinical radiopharmaceutical dosimetry

Preclinical dosimetry is essential for guiding the design of animal radiopharmaceutical biodistribution, imaging, and therapy experiments, evaluating efficacy and/or toxicities in such experiments, ensuring compliance with ethical standards for animal research, and providing reasonable initial estim...

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Detalles Bibliográficos
Autores principales: Carter, Lukas M., Zanzonico, Pat B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462246/
https://www.ncbi.nlm.nih.gov/pubmed/37645915
http://dx.doi.org/10.21203/rs.3.rs-3225362/v1
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author Carter, Lukas M.
Zanzonico, Pat B.
author_facet Carter, Lukas M.
Zanzonico, Pat B.
author_sort Carter, Lukas M.
collection PubMed
description Preclinical dosimetry is essential for guiding the design of animal radiopharmaceutical biodistribution, imaging, and therapy experiments, evaluating efficacy and/or toxicities in such experiments, ensuring compliance with ethical standards for animal research, and providing reasonable initial estimates of normal-organ doses in humans, required for clinical translation of new radiopharmaceuticals. This MIB guide provides a basic protocol for obtaining preclinical dosimetry estimates with organ-level dosimetry software.
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spelling pubmed-104622462023-08-29 MIB Guides: Preclinical radiopharmaceutical dosimetry Carter, Lukas M. Zanzonico, Pat B. Res Sq Article Preclinical dosimetry is essential for guiding the design of animal radiopharmaceutical biodistribution, imaging, and therapy experiments, evaluating efficacy and/or toxicities in such experiments, ensuring compliance with ethical standards for animal research, and providing reasonable initial estimates of normal-organ doses in humans, required for clinical translation of new radiopharmaceuticals. This MIB guide provides a basic protocol for obtaining preclinical dosimetry estimates with organ-level dosimetry software. American Journal Experts 2023-08-14 /pmc/articles/PMC10462246/ /pubmed/37645915 http://dx.doi.org/10.21203/rs.3.rs-3225362/v1 Text en https://creativecommons.org/licenses/by/4.0/This work is licensed under a Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/) , which allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, so long as attribution is given to the creator. The license allows for commercial use.
spellingShingle Article
Carter, Lukas M.
Zanzonico, Pat B.
MIB Guides: Preclinical radiopharmaceutical dosimetry
title MIB Guides: Preclinical radiopharmaceutical dosimetry
title_full MIB Guides: Preclinical radiopharmaceutical dosimetry
title_fullStr MIB Guides: Preclinical radiopharmaceutical dosimetry
title_full_unstemmed MIB Guides: Preclinical radiopharmaceutical dosimetry
title_short MIB Guides: Preclinical radiopharmaceutical dosimetry
title_sort mib guides: preclinical radiopharmaceutical dosimetry
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462246/
https://www.ncbi.nlm.nih.gov/pubmed/37645915
http://dx.doi.org/10.21203/rs.3.rs-3225362/v1
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