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Broadcasters, receivers, functional groups of metabolites and the link to heart failure progression using polygenic factors
In a prospective study with records of heart failure (HF) incidence, we present metabolite profiling data from individuals without HF at baseline. We uncovered the interconnectivity of metabolites using data-driven and causal networks augmented with polygenic factors. Exploring the networks, we iden...
Autores principales: | Yazdani, Azam, Mendez-Giraldez, Raul, Yazdani, Akram, Schaid, Daniel, Won Kong, Sek, Hadi, Mohamad, Samiei, Ahmad, Wittenbecher, Clemens, Lasky-Su, Jessica, Clish, Clary, Marotta, Francesco, Kosorok, Michael, Mora, Samia, Muehlschlegel, Jochen, Chasman, Daniel, Larson, Martin, Elsea, Sarah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462252/ https://www.ncbi.nlm.nih.gov/pubmed/37645766 http://dx.doi.org/10.21203/rs.3.rs-3246406/v1 |
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