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Multimodal Imaging in a Case of Chronic Sympathetic Ophthalmia
We report a case of chronic sympathetic ophthalmia (SO) in a one-eyed patient who was successfully managed with systemic immunosuppression therapy. A 77-year-old one-eyed female presented with progressive diminution of vision in the left eye (OS) for one month. She had previously undergone a right e...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462382/ https://www.ncbi.nlm.nih.gov/pubmed/37644926 http://dx.doi.org/10.7759/cureus.42645 |
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author | Chaturvedi, Abhijaat Parakh, Shweta Das, Shrutanjoy Bhatt, Vaibhav Luthra, Gaurav Luthra, Saurabh |
author_facet | Chaturvedi, Abhijaat Parakh, Shweta Das, Shrutanjoy Bhatt, Vaibhav Luthra, Gaurav Luthra, Saurabh |
author_sort | Chaturvedi, Abhijaat |
collection | PubMed |
description | We report a case of chronic sympathetic ophthalmia (SO) in a one-eyed patient who was successfully managed with systemic immunosuppression therapy. A 77-year-old one-eyed female presented with progressive diminution of vision in the left eye (OS) for one month. She had previously undergone a right eye (OD) pars plana vitrectomy elsewhere for exogenous post-operative endophthalmitis (after manual small incision cataract surgery five months ago), following which she developed phthisis. Granulomatous panuveitis and advanced cataract were noted in the OS. Findings on multimodal imaging, including spectral domain optical coherence tomography (SD-OCT), fundus fluorescein angiography (FFA), indocyanine green angiography (ICGA), and B-scan ultrasonography, were consistent with those of chronic SO. Promptly, oral steroids and systemic immunosuppressants were initiated under the supervision of a rheumatologist. At the three-week follow-up, complete resolution of clinical signs was observed on multimodal imaging. Chronic SO may present with ambiguous clinical signs, leading to a diagnostic dilemma. This may cause a delay in initiating treatment, which can prove to be highly detrimental, especially in one-eyed patients. Multimodal imaging is critical in excluding differential diagnoses and proves to be indispensable in the timely management of this sight-threatening condition. |
format | Online Article Text |
id | pubmed-10462382 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-104623822023-08-29 Multimodal Imaging in a Case of Chronic Sympathetic Ophthalmia Chaturvedi, Abhijaat Parakh, Shweta Das, Shrutanjoy Bhatt, Vaibhav Luthra, Gaurav Luthra, Saurabh Cureus Ophthalmology We report a case of chronic sympathetic ophthalmia (SO) in a one-eyed patient who was successfully managed with systemic immunosuppression therapy. A 77-year-old one-eyed female presented with progressive diminution of vision in the left eye (OS) for one month. She had previously undergone a right eye (OD) pars plana vitrectomy elsewhere for exogenous post-operative endophthalmitis (after manual small incision cataract surgery five months ago), following which she developed phthisis. Granulomatous panuveitis and advanced cataract were noted in the OS. Findings on multimodal imaging, including spectral domain optical coherence tomography (SD-OCT), fundus fluorescein angiography (FFA), indocyanine green angiography (ICGA), and B-scan ultrasonography, were consistent with those of chronic SO. Promptly, oral steroids and systemic immunosuppressants were initiated under the supervision of a rheumatologist. At the three-week follow-up, complete resolution of clinical signs was observed on multimodal imaging. Chronic SO may present with ambiguous clinical signs, leading to a diagnostic dilemma. This may cause a delay in initiating treatment, which can prove to be highly detrimental, especially in one-eyed patients. Multimodal imaging is critical in excluding differential diagnoses and proves to be indispensable in the timely management of this sight-threatening condition. Cureus 2023-07-29 /pmc/articles/PMC10462382/ /pubmed/37644926 http://dx.doi.org/10.7759/cureus.42645 Text en Copyright © 2023, Chaturvedi et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Ophthalmology Chaturvedi, Abhijaat Parakh, Shweta Das, Shrutanjoy Bhatt, Vaibhav Luthra, Gaurav Luthra, Saurabh Multimodal Imaging in a Case of Chronic Sympathetic Ophthalmia |
title | Multimodal Imaging in a Case of Chronic Sympathetic Ophthalmia |
title_full | Multimodal Imaging in a Case of Chronic Sympathetic Ophthalmia |
title_fullStr | Multimodal Imaging in a Case of Chronic Sympathetic Ophthalmia |
title_full_unstemmed | Multimodal Imaging in a Case of Chronic Sympathetic Ophthalmia |
title_short | Multimodal Imaging in a Case of Chronic Sympathetic Ophthalmia |
title_sort | multimodal imaging in a case of chronic sympathetic ophthalmia |
topic | Ophthalmology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462382/ https://www.ncbi.nlm.nih.gov/pubmed/37644926 http://dx.doi.org/10.7759/cureus.42645 |
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