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4-PBA inhibits endoplasmic reticulum stress to improve autophagic flux in the treatment of protamine/lipopolysaccharide-induced interstitial cystitis in rats

Interstitial cystitis (IC) has severe clinical symptoms with unclear mechanism. The continuous inflammatory response of the bladder is the basis of its pathogenesis. Endoplasmic reticulum stress (ERS) is involved in the regulation and development of various inflammatory diseases. And autophagy plays...

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Detalles Bibliográficos
Autores principales: Jia, Li, Jingzhen, Zhu, Xinliang, Yang, Bishao, Sun, Xin, Luo, Ji, Zheng, Zhenqiang, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462651/
https://www.ncbi.nlm.nih.gov/pubmed/37640742
http://dx.doi.org/10.1038/s41598-023-38584-x