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SARS-CoV-2 spike protein induces endothelial inflammation via ACE2 independently of viral replication

COVID-19, caused by SARS-CoV-2, is a respiratory disease associated with inflammation and endotheliitis. Mechanisms underling inflammatory processes are unclear, but angiotensin converting enzyme 2 (ACE2), the receptor which binds the spike protein of SARS-CoV-2 may be important. Here we investigate...

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Detalles Bibliográficos
Autores principales:	Montezano, Augusto C., Camargo, Livia L., Mary, Sheon, Neves, Karla B, Rios, Francisco J, Stein, Ross, Lopes, Rheure A., Beattie, Wendy, Thomson, Jacqueline, Herder, Vanessa, Szemiel, Agnieszka M., McFarlane, Steven, Palmarini, Massimo, Touyz, Rhian M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462711/ https://www.ncbi.nlm.nih.gov/pubmed/37640791 http://dx.doi.org/10.1038/s41598-023-41115-3

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