P2X7 purinergic receptor modulates dentate gyrus excitatory neurotransmission and alleviates schizophrenia-like symptoms in mouse

ATP-gated P2X7 receptors (P2X7Rs) play a crucial role in brain disorders. However, how they affect normal and pathological synaptic transmission is still largely unclear. Here, by using whole-cell patch-clamp technique to record AMPA- and NMDA receptor-mediated excitatory postsynaptic currents (s/mE...

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Detalles Bibliográficos
Autores principales: Huang, Lumei, Mut-Arbona, Paula, Varga, Bernadett, Török, Bibiana, Brunner, János, Arszovszki, Antonia, Iring, András, Kisfali, Máté, Vizi, E. Sylvester, Sperlágh, Beáta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462828/
https://www.ncbi.nlm.nih.gov/pubmed/37649698
http://dx.doi.org/10.1016/j.isci.2023.107560

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