Recognition determinants of improved HIV-1 neutralization by a heavy chain matured pediatric antibody

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The structural and characteristic features of HIV-1 broadly neutralizing antibodies (bnAbs) from chronically infected pediatric donors are currently unknown. Herein, we characterized a heavy chain matured HIV-1 bnAb 44m, identified from a pediatric elite-neutralizer. Interestingly, in comparison to...

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Detalles Bibliográficos
Autores principales: Kumar, Sanjeev, Singh, Swarandeep, Chatterjee, Arnab, Bajpai, Prashant, Sharma, Shaifali, Katpara, Sanket, Lodha, Rakesh, Dutta, Somnath, Luthra, Kalpana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462834/
https://www.ncbi.nlm.nih.gov/pubmed/37649696
http://dx.doi.org/10.1016/j.isci.2023.107579

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