Cargando…
Sex- and age-dependent contribution of System x(c)(–) to cognitive, sensory, and social behaviors revealed by comprehensive behavioral analyses of System x(c)(–) null mice
BACKGROUND: System x(c)(–) (Sx(c)(–)) is an important heteromeric amino acid cystine/glutamate exchanger that plays a pivotal role in the CNS by importing cystine into cells while exporting glutamate. Although certain behaviors have been identified as altered in Sx(c)(–) null mutant mice, our unders...
Autores principales: | Frare, Carla, Pitt, Shannon K., Hewett, Sandra J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462982/ https://www.ncbi.nlm.nih.gov/pubmed/37649973 http://dx.doi.org/10.3389/fnbeh.2023.1238349 |
Ejemplares similares
-
Non-cell autonomous influence of the astrocyte system x(c)(−) on hypoglycaemic neuronal cell death
por: Jackman, Nicole A, et al.
Publicado: (2012) -
The Cystine/Glutamate Antiporter, System x(c)(–), Contributes to Cortical Infarction After Moderate but Not Severe Focal Cerebral Ischemia in Mice
por: He, Yan, et al.
Publicado: (2022) -
X-ray perception: Animal studies of sensory and behavioral responses to X-rays
por: Mantraratnam, Vaishnavi, et al.
Publicado: (2022) -
RGS4 deficit in prefrontal cortex contributes to the behaviors related to schizophrenia via system x(c)(-)-mediated glutamatergic dysfunction in mice
por: Huang, Min-Wei, et al.
Publicado: (2018) -
Decreased epileptogenesis in mice lacking the System x(c)
(−) transporter occurs in association with a reduction in AMPA receptor subunit GluA1
por: Sears, Sheila M. S., et al.
Publicado: (2019)