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Sex- and age-dependent contribution of System x(c)(–) to cognitive, sensory, and social behaviors revealed by comprehensive behavioral analyses of System x(c)(–) null mice

BACKGROUND: System x(c)(–) (Sx(c)(–)) is an important heteromeric amino acid cystine/glutamate exchanger that plays a pivotal role in the CNS by importing cystine into cells while exporting glutamate. Although certain behaviors have been identified as altered in Sx(c)(–) null mutant mice, our unders...

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Detalles Bibliográficos
Autores principales: Frare, Carla, Pitt, Shannon K., Hewett, Sandra J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462982/
https://www.ncbi.nlm.nih.gov/pubmed/37649973
http://dx.doi.org/10.3389/fnbeh.2023.1238349

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