Growth hormone-releasing hormone antagonist MIA-602 inhibits inflammation induced by SARS-CoV-2 spike protein and bacterial lipopolysaccharide synergism in macrophages and human peripheral blood mononuclear cells

COVID-19 is characterized by an excessive inflammatory response and macrophage hyperactivation, leading, in severe cases, to alveolar epithelial injury and acute respiratory distress syndrome. Recent studies have reported that SARS-CoV-2 spike (S) protein interacts with bacterial lipopolysaccharide...

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Detalles Bibliográficos
Autores principales: Granato, Giuseppina, Gesmundo, Iacopo, Pedrolli, Francesca, Kasarla, Ramesh, Begani, Laura, Banfi, Dana, Bruno, Stefania, Lopatina, Tatiana, Brizzi, Maria Felice, Cai, Renzhi, Sha, Wei, Ghigo, Ezio, Schally, Andrew V., Granata, Riccarda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10462983/
https://www.ncbi.nlm.nih.gov/pubmed/37649486
http://dx.doi.org/10.3389/fimmu.2023.1231363

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