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Efficient NADPH-dependent dehalogenation afforded by a self-sufficient reductive dehalogenase

Reductive dehalogenases are corrinoid and iron–sulfur cluster–containing enzymes that catalyze the reductive removal of a halogen atom. The oxygen-sensitive and membrane-associated nature of the respiratory reductive dehalogenases has hindered their detailed kinetic study. In contrast, the evolution...

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Detalles Bibliográficos
Autores principales: Fisher, Karl, Halliwell, Tom, Payne, Karl A.P., Ragala, Gabriel, Hay, Sam, Rigby, Stephen E.J., Leys, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463259/
https://www.ncbi.nlm.nih.gov/pubmed/37495113
http://dx.doi.org/10.1016/j.jbc.2023.105086