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Prompt treatment-seeking behaviour varies within communities among guardians of children with malaria-related fever in Malawi
BACKGROUND: In Malawi, malaria is responsible for 40% of hospital deaths. Prompt diagnosis and effective treatment within 24 h of fever onset is critical to prevent progression from uncomplicated to severe disease and to reduce transmission. METHODS: As part of the large evaluation of the malaria va...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463323/ https://www.ncbi.nlm.nih.gov/pubmed/37633902 http://dx.doi.org/10.1186/s12936-023-04680-6 |
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author | Stanley, Christopher C. Chirombo, James Msuku, Harrison Phiri, Vincent S. Patson, Noel Kazembe, Lawrence N. Chinkhumba, Jobiba Kapito-Tembo, Atupele Mathanga, Don P. |
author_facet | Stanley, Christopher C. Chirombo, James Msuku, Harrison Phiri, Vincent S. Patson, Noel Kazembe, Lawrence N. Chinkhumba, Jobiba Kapito-Tembo, Atupele Mathanga, Don P. |
author_sort | Stanley, Christopher C. |
collection | PubMed |
description | BACKGROUND: In Malawi, malaria is responsible for 40% of hospital deaths. Prompt diagnosis and effective treatment within 24 h of fever onset is critical to prevent progression from uncomplicated to severe disease and to reduce transmission. METHODS: As part of the large evaluation of the malaria vaccine implementation programme (MVIP), this study analysed survey data to investigate whether prompt treatment-seeking behaviour is clustered at community-level according to socio-economic demographics. RESULTS: From 4563 households included in the survey, 4856 children aged 5–48 months were enrolled. Out of 4732 children with documented gender, 52.2% were female and 47.8% male. Among the 4856 children, 33.8% reported fever in the two weeks prior to the survey. Fever prevalence was high in communities with low socio-economic status (SES) (38.3% [95% CI: 33.7–43.5%]) and low in areas with high SES (29.8% [95% CI: 25.6–34.2%]). Among children with fever, 648 (39.5%) sought treatment promptly i.e., within 24 h from onset of fever symptoms. Children were more likely to be taken for prompt treatment among guardians with secondary education compared to those without formal education (aOR:1.37, 95% CI: 1.11–3.03); in communities with high compared to low SES [aOR: 2.78, 95% CI: 1.27–6.07]. Children were less likely to be taken for prompt treatment if were in communities far beyond 5 km to health facility than within 5 km [aOR: 0.44, 95% CI: 0.21–0.92]. CONCLUSION: The high heterogeneity in prevalence of fever and levels of prompt treatment-seeking behaviour underscore the need to promote community-level malaria control interventions (such as use of long-lasting insecticide-treated nets (LLINs), indoor residual spraying (IRS), intermittent preventive therapy (IPT), presumptive treatment and education). Programmes aimed at improving treatment-seeking behaviour should consider targeting communities with low SES and those far from health facility. |
format | Online Article Text |
id | pubmed-10463323 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-104633232023-08-30 Prompt treatment-seeking behaviour varies within communities among guardians of children with malaria-related fever in Malawi Stanley, Christopher C. Chirombo, James Msuku, Harrison Phiri, Vincent S. Patson, Noel Kazembe, Lawrence N. Chinkhumba, Jobiba Kapito-Tembo, Atupele Mathanga, Don P. Malar J Research BACKGROUND: In Malawi, malaria is responsible for 40% of hospital deaths. Prompt diagnosis and effective treatment within 24 h of fever onset is critical to prevent progression from uncomplicated to severe disease and to reduce transmission. METHODS: As part of the large evaluation of the malaria vaccine implementation programme (MVIP), this study analysed survey data to investigate whether prompt treatment-seeking behaviour is clustered at community-level according to socio-economic demographics. RESULTS: From 4563 households included in the survey, 4856 children aged 5–48 months were enrolled. Out of 4732 children with documented gender, 52.2% were female and 47.8% male. Among the 4856 children, 33.8% reported fever in the two weeks prior to the survey. Fever prevalence was high in communities with low socio-economic status (SES) (38.3% [95% CI: 33.7–43.5%]) and low in areas with high SES (29.8% [95% CI: 25.6–34.2%]). Among children with fever, 648 (39.5%) sought treatment promptly i.e., within 24 h from onset of fever symptoms. Children were more likely to be taken for prompt treatment among guardians with secondary education compared to those without formal education (aOR:1.37, 95% CI: 1.11–3.03); in communities with high compared to low SES [aOR: 2.78, 95% CI: 1.27–6.07]. Children were less likely to be taken for prompt treatment if were in communities far beyond 5 km to health facility than within 5 km [aOR: 0.44, 95% CI: 0.21–0.92]. CONCLUSION: The high heterogeneity in prevalence of fever and levels of prompt treatment-seeking behaviour underscore the need to promote community-level malaria control interventions (such as use of long-lasting insecticide-treated nets (LLINs), indoor residual spraying (IRS), intermittent preventive therapy (IPT), presumptive treatment and education). Programmes aimed at improving treatment-seeking behaviour should consider targeting communities with low SES and those far from health facility. BioMed Central 2023-08-26 /pmc/articles/PMC10463323/ /pubmed/37633902 http://dx.doi.org/10.1186/s12936-023-04680-6 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Stanley, Christopher C. Chirombo, James Msuku, Harrison Phiri, Vincent S. Patson, Noel Kazembe, Lawrence N. Chinkhumba, Jobiba Kapito-Tembo, Atupele Mathanga, Don P. Prompt treatment-seeking behaviour varies within communities among guardians of children with malaria-related fever in Malawi |
title | Prompt treatment-seeking behaviour varies within communities among guardians of children with malaria-related fever in Malawi |
title_full | Prompt treatment-seeking behaviour varies within communities among guardians of children with malaria-related fever in Malawi |
title_fullStr | Prompt treatment-seeking behaviour varies within communities among guardians of children with malaria-related fever in Malawi |
title_full_unstemmed | Prompt treatment-seeking behaviour varies within communities among guardians of children with malaria-related fever in Malawi |
title_short | Prompt treatment-seeking behaviour varies within communities among guardians of children with malaria-related fever in Malawi |
title_sort | prompt treatment-seeking behaviour varies within communities among guardians of children with malaria-related fever in malawi |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463323/ https://www.ncbi.nlm.nih.gov/pubmed/37633902 http://dx.doi.org/10.1186/s12936-023-04680-6 |
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