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5ʹ-Ectonucleotidase CD73/NT5E supports EGFR-mediated invasion of HPV-negative head and neck carcinoma cells

BACKGROUND: Epithelial-to-mesenchymal transition (EMT) of malignant cells is a driving force of disease progression in human papillomavirus-negative (HPV-negative) head and neck squamous cell carcinomas (HNSCC). Sustained hyper-activation of epidermal growth factor receptor (EGFR) induces an invasio...

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Detalles Bibliográficos
Autores principales: Shi, Enxian, Wu, Zhengquan, Karaoglan, Birnur Sinem, Schwenk-Zieger, Sabina, Kranz, Gisela, Abdul Razak, Nilofer, Reichel, Christoph A., Canis, Martin, Baumeister, Philipp, Zeidler, Reinhard, Gires, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463398/
https://www.ncbi.nlm.nih.gov/pubmed/37620936
http://dx.doi.org/10.1186/s12929-023-00968-6