Mutations in CCNB3 affect its location thus causing a multiplicity of phenotypes in human oocytes maturation by aberrant CDK1 activity and APC/C activity at different stages

BACKGROUND: Oocyte maturation arrest results in female infertility and the genetic etiology of this phenotype remains largely unknown. Previous studies have proven that cyclins play a significant role in the cell cycle both in meiosis and mitosis. Cyclin B3 (CCNB3) is one of the members of the cycli...

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Detalles Bibliográficos
Autores principales: Wang, Congjing, Chen, Meng Xi, Zhang, Yuan, Bai, Xue, Cao, Qiqi, Han, Jian, Zhang, Nana, Zhao, Chun, Ling, Xiufeng, Rui, Ximan, Guan, Yichun, Zhang, Junqiang, Huo, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463413/
https://www.ncbi.nlm.nih.gov/pubmed/37635245
http://dx.doi.org/10.1186/s13048-023-01229-8

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