Glucocorticoid regulation of the mTORC1 pathway modulates CD4(+) T cell responses during infection

OBJECTIVES: Conventional glucocorticoid (GC) treatment poses significant risks for opportunistic infections due to its suppressive impact on CD4(+) T cells. This study aimed to explore the mechanisms by which GCs modulate the functionality of CD4(+) T cells during infection. METHODS: We consistently...

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Detalles Bibliográficos
Autores principales: Chen, Huihui, Liu, Zhiwen, Zha, Jie, Zeng, Li, Tang, Runyan, Tang, Chengyuan, Cai, Juan, Tan, Chongqing, Liu, Hong, Dong, Zheng, Chen, Guochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463561/
https://www.ncbi.nlm.nih.gov/pubmed/37649974
http://dx.doi.org/10.1002/cti2.1464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463561/
https://www.ncbi.nlm.nih.gov/pubmed/37649974
http://dx.doi.org/10.1002/cti2.1464

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