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Predicting weighted unobserved nodes in a regulatory network using answer set programming
BACKGROUND: The impact of a perturbation, over-expression, or repression of a key node on an organism, can be modelled based on a regulatory and/or metabolic network. Integration of these two networks could improve our global understanding of biological mechanisms triggered by a perturbation. This s...
Autores principales: | Le Bars, Sophie, Bolteau, Mathieu, Bourdon, Jérémie, Guziolowski, Carito |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463596/ https://www.ncbi.nlm.nih.gov/pubmed/37626282 http://dx.doi.org/10.1186/s12859-023-05429-3 |
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