Cargando…

Prolyl oligopeptidase inhibition ameliorates experimental pulmonary fibrosis both in vivo and in vitro

BACKGROUND: Pulmonary fibrosis is a progressive disease characterized by lung remodeling due to excessive deposition of extracellular matrix. Although the etiology remains unknown, aberrant angiogenesis and inflammation play an important role in the development of this pathology. In this context, re...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cucinotta, Laura, Mannino, Deborah, Casili, Giovanna, Repici, Alberto, Crupi, Lelio, Paterniti, Irene, Esposito, Emanuela, Campolo, Michela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463606/ https://www.ncbi.nlm.nih.gov/pubmed/37626373 http://dx.doi.org/10.1186/s12931-023-02519-x

Ejemplares similares

Inhibition of Prolyl Oligopeptidase Prevents Consequences of Reperfusion following Intestinal Ischemia
por: Filippone, Alessia, et al.
Publicado: (2021)

The protective role of prolyl oligopeptidase (POP) inhibition in acute lung injury induced by intestinal ischemia-reperfusion
por: Casili, Giovanna, et al.
Publicado: (2021)

The Protective Role of Prolyl Oligopeptidase (POP) Inhibition in Kidney Injury Induced by Renal Ischemia–Reperfusion
por: Casili, Giovanna, et al.
Publicado: (2021)

The Inhibition of Prolyl Oligopeptidase as New Target to Counteract Chronic Venous Insufficiency: Findings in a Mouse Model
por: Casili, Giovanna, et al.
Publicado: (2020)

KYP-2047, an Inhibitor of Prolyl-Oligopeptidase, Reduces GlioBlastoma Proliferation through Angiogenesis and Apoptosis Modulation
por: Scuderi, Sarah Adriana, et al.
Publicado: (2021)

LRRK2 Inhibition by PF06447475 Antagonist Modulates Early Neuronal Damage after Spinal Cord Trauma
por: Filippone, Alessia, et al.
Publicado: (2022)

Dimethyl Fumarate (DMF) Alleviated Post-Operative (PO) Pain through the N-Methyl-d-Aspartate (NMDA) Receptors
por: Casili, Giovanna, et al.
Publicado: (2022)

Adenosine Targeting as a New Strategy to Decrease Glioblastoma Aggressiveness
por: Bova, Valentina, et al.
Publicado: (2022)

Neuroprotective effects of GSK-343 in an in vivo model of MPTP-induced nigrostriatal degeneration
por: Mannino, Deborah, et al.
Publicado: (2023)

Inhibition of LRRK2 Attenuates Depression-Related Symptoms in Mice with Moderate Traumatic Brain Injury
por: Filippone, Alessia, et al.
Publicado: (2023)

Beneficial effect of KYP-2047, a propyl-oligopeptidase inhibitor, on oral squamous cell carcinoma
por: Scuderi, Sarah Adriana, et al.
Publicado: (2021)

The role of prolyl oligopeptidase, understanding the puzzle
por: García-Horsman, J. Arturo
Publicado: (2020)

Potential Therapeutic Effects of PPAR Ligands in Glioblastoma
por: Basilotta, Rossella, et al.
Publicado: (2022)

A Combination of Xyloglucan, Pea Protein and Chia Seed Ameliorates Intestinal Barrier Integrity and Mucosa Functionality in a Rat Model of Constipation-Predominant Irritable Bowel Syndrome
por: Filippone, Alessia, et al.
Publicado: (2022)

Ulva pertusa, a Marine Green Alga, Attenuates DNBS-Induced Colitis Damage via NF-κB/Nrf2/SIRT1 Signaling Pathways
por: Ardizzone, Alessio, et al.
Publicado: (2022)

The Prognostic Value of Pentraxin-3 in COVID-19 Patients: A Systematic Review and Meta-Analysis of Mortality Incidence
por: Capra, Anna Paola, et al.
Publicado: (2023)

Efficacy of a Product Containing Xyloglucan and Pea Protein on Intestinal Barrier Function in a Partial Restraint Stress Animal Model
por: Scuderi, Sarah Adriana, et al.
Publicado: (2022)

The Transcription Factor Nrf2 Mediates the Effects of Antrodia camphorata Extract on Neuropathological Changes in a Mouse Model of Parkinson’s Disease
por: Lanza, Marika, et al.
Publicado: (2023)

SUN11602, a bFGF mimetic, modulated neuroinflammation, apoptosis and calcium-binding proteins in an in vivo model of MPTP-induced nigrostriatal degeneration
por: Ardizzone, Alessio, et al.
Publicado: (2022)

Multiple mechanisms of dimethyl fumarate in amyloid β‐induced neurotoxicity in human neuronal cells
por: Campolo, Michela, et al.
Publicado: (2017)

The Anti-Inflammatory and Antioxidant Effects of Sodium Propionate
por: Filippone, Alessia, et al.
Publicado: (2020)

Dimethyl fumarate alleviates the nitroglycerin (NTG)-induced migraine in mice
por: Casili, Giovanna, et al.
Publicado: (2020)

Evaluating the Protective Properties of a Xyloglucan-Based Nasal Spray in a Mouse Model of Allergic Rhinitis
por: Lanza, Marika, et al.
Publicado: (2021)

SCFA Treatment Alleviates Pathological Signs of Migraine and Related Intestinal Alterations in a Mouse Model of NTG-Induced Migraine
por: Lanza, Marika, et al.
Publicado: (2021)

Efficacy of a Novel Therapeutic, Based on Natural Ingredients and Probiotics, in a Murine Model of Multiple Food Intolerance and Maldigestion
por: Ardizzone, Alessio, et al.
Publicado: (2022)

A New Approach for the Treatment of Recurrent Vulvovaginal Candidiasis with a Combination of Pea Protein, Grape Seed Extract, and Lactic Acid Assessed In Vivo
por: Paterniti, Irene, et al.
Publicado: (2022)

Modulation of NLRP3 Inflammasome Attenuated Inflammatory Response Associated to Diarrhea-Predominant Irritable Bowel Syndrome
por: Scuderi, Sarah Adriana, et al.
Publicado: (2020)

Prolyl oligopeptidase is inhibited in relapsing-remitting multiple sclerosis
por: Tenorio-Laranga, Jofre, et al.
Publicado: (2010)

Prolyl Oligopeptidase, Inositol Phosphate Signalling and Lithium Sensitivity
por: Harwood, Adrian J
Publicado: (2011)

Removal of prolyl oligopeptidase reduces alpha-synuclein toxicity in cells and in vivo
por: Svarcbahs, Reinis, et al.
Publicado: (2018)

GSK343, an Inhibitor of Enhancer of Zeste Homolog 2, Reduces Glioblastoma Progression through Inflammatory Process Modulation: Focus on Canonical and Non-Canonical NF-κB/IκBα Pathways
por: Scuderi, Sarah Adriana, et al.
Publicado: (2022)

FeTPPS Reduces Secondary Damage and Improves Neurobehavioral Functions after Traumatic Brain Injury
por: Bruschetta, Giuseppe, et al.
Publicado: (2017)

Effect of a combination of pea protein, grape seed extract and lactic acid in an in vivo model of bacterial vaginosis
por: Lanza, Marika, et al.
Publicado: (2023)

Therapeutic Potential of Dimethyl Fumarate in Counteract Oral Squamous Cell Carcinoma Progression by Modulating Apoptosis, Oxidative Stress and Epithelial–Mesenchymal Transition
por: Basilotta, Rossella, et al.
Publicado: (2023)

TLR7/8 in the Pathogenesis of Parkinson’s Disease †
por: Campolo, Michela, et al.
Publicado: (2020)

Kinetic Landscape of a Peptide Bond-Forming Prolyl Oligopeptidase
por: Czekster, Clarissa M., et al.
Publicado: (2017)

Intrinsic basis of thermostability of prolyl oligopeptidase from Pyrococcus furiosus
por: Banerjee, Sahini, et al.
Publicado: (2021)

Crystal Structures of Trypanosoma brucei Oligopeptidase B Broaden the Paradigm of Catalytic Regulation in Prolyl Oligopeptidase Family Enzymes
por: Canning, Peter, et al.
Publicado: (2013)

The Pivotal Role of Protein Phosphatase 2A (PP2A) in Brain Tumors
por: Cucinotta, Laura, et al.
Publicado: (2022)

Sodium Propionate Contributes to Tumor Cell Growth Inhibition through PPAR-γ Signaling
por: Filippone, Alessia, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_3tr330ofjjhshu9fn3037cjp70