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Pan-cancer analysis identifies SPEN mutation as a predictive biomarker with the efficacy of immunotherapy

The association between specific genetic mutations and immunotherapy benefits has been widely known, while such studies in pan-cancer are still limited. SPEN, mainly involved in X chromosome inactivation (XCI), plays an essential in tumorigenesis and sex differences in cancer. Thus, we firstly analy...

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Detalles Bibliográficos
Autores principales:	Li, Ya-Dong, Huang, Hao, Ren, Zheng-Ju, Yuan, Ye, Wu, Hao, Liu, Chuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463702/ https://www.ncbi.nlm.nih.gov/pubmed/37620924 http://dx.doi.org/10.1186/s12885-023-11235-0

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