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Extracellular matrix turnover biomarkers reflect pharmacodynamic effects and treatment response of adalimumab in patients with axial spondyloarthritis—results from two randomized controlled trials

OBJECTIVE: To investigate if extracellular matrix (ECM) blood-based biomarkers reflect the pharmacodynamic effect and response to TNF-α inhibitor therapy (adalimumab, ADA), in patients with axial spondyloarthritis (axSpA). METHODS: We investigated ECM biomarkers in two randomized, double-blind, plac...

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Detalles Bibliográficos
Autores principales:	Port, Helena, Holm Nielsen, Signe, Frederiksen, Peder, Madsen, Sofie Falkenløve, Bay-Jensen, Anne-Christine, Sørensen, Inge Juul, Jensen, Bente, Loft, Anne Gitte, Madsen, Ole Rintek, Østergaard, Mikkel, Pedersen, Susanne Juhl
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463764/ https://www.ncbi.nlm.nih.gov/pubmed/37626399 http://dx.doi.org/10.1186/s13075-023-03132-5

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