Exosomal ACADM sensitizes gemcitabine-resistance through modulating fatty acid metabolism and ferroptosis in pancreatic cancer

This study aimed to evaluate the potential of exosomes from cancer cells to predict chemoresistance in pancreatic cancer (PC) and explore the molecular mechanisms through RNA-sequencing and mass spectrometry. We sought to understand the connection between the exosomal Medium-chain acyl-CoA dehydroge...

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Detalles Bibliográficos
Autores principales: Yang, Yuhan, Gu, Haitao, Zhang, Kundong, Guo, Zengya, Wang, Xiaofeng, Wei, Qingyun, Weng, Ling, Han, Xuan, Lv, Yan, Cao, Meng, Cao, Peng, Huang, Chen, Qiu, Zhengjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463774/
https://www.ncbi.nlm.nih.gov/pubmed/37612627
http://dx.doi.org/10.1186/s12885-023-11239-w

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