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Ceramide synthesis regulates biogenesis and packaging of exosomal MALAT1 from adipose derived stem cells, increases dermal fibroblast migration and mitochondrial function

BACKGROUND: The function of exosomes, small extracellular vesicles (sEV) secreted from human adipose-derived stem cells (ADSC), is becoming increasingly recognized as a means of transferring the regenerative power of stem cells to injured cells in wound healing. Exosomes are rich in ceramides and lo...

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Detalles Bibliográficos
Autores principales: Kong, Xaioyuan, Patel, Niketa A., Chalfant, Charles E., Cooper, Denise R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463839/
https://www.ncbi.nlm.nih.gov/pubmed/37620957
http://dx.doi.org/10.1186/s12964-022-00900-9