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Inhibiting NLRP3 inflammasome signaling pathway promotes neurological recovery following hypoxic-ischemic brain damage by increasing p97-mediated surface GluA1-containing AMPA receptors

BACKGROUND: The nucleotide-binding oligomeric domain (NOD)-like receptor protein 3 (NLRP3) inflammasome is believed to be a key mediator of neuroinflammation and subsequent secondary brain injury induced by ischemic stroke. However, the role and underlying mechanism of the NLRP3 inflammasome in neon...

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Detalles Bibliográficos
Autores principales:	Chen, Yuxin, Li, Xiaohuan, Xiong, Qian, Du, Yehong, Luo, Man, Yi, Lilin, Pang, Yayan, Shi, Xiuyu, Wang, Yu Tian, Dong, Zhifang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463885/ https://www.ncbi.nlm.nih.gov/pubmed/37620837 http://dx.doi.org/10.1186/s12967-023-04452-5

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