Discrimination of SARS-CoV-2 omicron variant and its lineages by rapid detection of immune-escape mutations in spike protein RBD using asymmetric PCR-based melting curve analysis

BACKGROUND: The SARS-CoV-2 Omicron strain has multiple immune-escape mutations in the spike protein receptor-binding domain (RBD). Rapid detection of these mutations to identify Omicron and its lineages is essential for guiding public health strategies and patient treatments. We developed a two-tube...

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Detalles Bibliográficos
Autores principales: Kong, Xiaomu, Gao, Peng, Jiang, Yongwei, Lu, Lixia, Zhao, Meimei, Liu, Yi, Deng, Guoxiong, Zhu, Haoyan, Cao, Yongtong, Ma, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10463914/
https://www.ncbi.nlm.nih.gov/pubmed/37626353
http://dx.doi.org/10.1186/s12985-023-02137-5

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